Neuromusculoskeletal Medicine

Stem Cell Study Suggests Novel Mechanism of Action in Knee Osteoarthritis

Autologous bone marrow mesenchymal stromal cells (MSCs) are safe and efficacious in treating knee osteoarthritis (OA), and — in an apparently novel finding — they may reduce inflammation and modulate immune cells that contribute to the condition, Canadian researchers report.


Degenerative Disease in Profile

Degenerative conditions burden millions of Americans physically, financially and emotionally. These numbers help tell the story.


Study of Cannabinoids’ Potential to Treat MS Symptoms Yields Mixed Results

Medicinal cannabinoids are likely safe for individuals with multiple sclerosis (MS), but the drugs’ efficacy in relieving symptoms appears to be slight, a recent systematic review and meta-analysis finds.


Stimulation Aids Spinal Cord Injury Patients’ Bladder Control

Five men with spinal cord injuries that impaired the ability to voluntarily urinate gained improved bladder control as well as average quality-of-life improvement of 60 percent after lower-spinal-cord stimulation, according to a study in Scientific Reports.


Orthopedic Spotlight

About half of U.S. adults have a musculoskeletal condition, creating well over $200 billion in lost wages and costs for care each year. In addition, many orthopedists face a staggering clinical and bureaucratic workload.


Findings on Physician-assisted Suicide Suggest Need to Address Depression in MS Patients

A survey of people with multiple sclerosis reveals significant interest in physician-assisted suicide — findings that highlight the value of dealing with mental health issues among this population, according to researchers.


Link between ALS, Schizophrenia May Spur New Paths of Research

Amyotrophic lateral sclerosis and schizophrenia share genetic origins, according to recent research published in Nature Communications. That finding has the potential to change how neurological and psychiatric diseases are studied and furthers hopes of curing both conditions.


That's News

Treatment Restores Movement to Mouse Models of MS

By teaching T cells not to attack neurons’ myelin sheath, University of Maryland researchers believe they could be on a path toward improved approaches to diseases such as multiple sclerosis.

An experimental treatment injected...


A Way Forward in Treating Primary-Progressive Multiple Sclerosis?

The lack of a medication to treat primary-progressive multiple sclerosis (PPMS) is a source of frustration for clinicians and patients. The results of a recent phase 3 study of the drug ocrelizumab may be cause for hope.


PUMA Pressure Ulcer Risk Detection

People who have tetraplegic spinal cord injury may not always realize when they are developing pressure ulcers. Now, a research project in Europe, Pressure Ulcer Measurement and Actuation (PUMA), has developed a device that assesses risk for pressure ulcers and suggests strategies to address that risk.